Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378766 | 0.98 | KMT2A (0.55) | KMT2ADAOMCL1MEN1NPC1 | |
| SCHEMBL154592 | 0.98 | KMT2A (0.55) | KMT2ADAOMCL1MEN1NPC1 | |
| Cyanide SCHEMBL6526282 | 0.91 | KMT2A (0.50) | KMT2ADAOMCL1MEN1NPC1 | |
| SCHEMBL5700702 | 0.90 | KMT2A (0.53) | KMT2ADAOMCL1MEN1NPC1 | |
| SCHEMBL1172151 | 0.90 | KMT2A (0.53) | KMT2ADAOMCL1MEN1NPC1 | |
| SCHEMBL29528615 | 0.90 | KMT2A (0.53) | KMT2ADAOMCL1MEN1NPC1 | |
| SCHEMBL5700705 | 0.86 | DAO (0.47) | KMT2ADAOMCL1MEN1NPC1 | |
| Formamide SCHEMBL8533326 | 0.86 | DAO (0.47) | KMT2ADAOMCL1MEN1NPC1 | |
| SCHEMBL1172147 | 0.86 | DAO (0.47) | KMT2ADAOMCL1MEN1NPC1 | |
| SCHEMBL27898683 | 0.86 | DAO (0.47) | KMT2ADAOMCL1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829550-A | Pyrimidine-2-ylsulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-110526912-B | Heteroaryl compounds for kinase inhibition | 武田药品工业株式会社 | 2023-02-14 | — | — | CN | disclosed |
| CN-106559991-A | Heteroaryl compounds for kinase inhibition | 阿里亚德医药股份有限公司 | 2017-04-05 | — | — | CN | disclosed |