Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nonane SCHEMBL28044830 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Nonacosane SCHEMBL28201695 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Pentadecane SCHEMBL28134975 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL28134147 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Tridecane SCHEMBL28134974 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Decane SCHEMBL27285858 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL28246815 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL28132819 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL27706945 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Undecane SCHEMBL27485945 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660943-A | Metal/radiometal labeled PSMA inhibitors for PSMA-targeted imaging and radiotherapy | 约翰霍普金斯大学 | 2017-05-10 | — | — | CN | disclosed |