Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28147198 | 1.00 | — | — | |
| Bicarbonate SCHEMBL10742520 | 1.00 | CA1 (0.60) | — | |
| Bicarbonate SCHEMBL9637401 | 0.95 | CA1 (0.67) | — | |
| Bicarbonate SCHEMBL6033140 | 0.95 | — | — | |
| Bicarbonate SCHEMBL28225162 | 0.90 | — | — | |
| Nitrous Acid SCHEMBL11883017 | 0.84 | CA1 (0.86) | — | |
| Nitrous Acid SCHEMBL624195 | 0.84 | CA1 (0.86) | — | |
| Nitrous Acid SCHEMBL28383116 | 0.84 | — | — | |
| Nitrous Acid SCHEMBL2348981 | 0.84 | — | — | |
| Nitrous Acid SCHEMBL6241289 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108300736-A | The Chinese hamster ovary celI strain of efficiently expressing recombinant human β-NGF-Fc fusion proteins and its construction method | 中国食品药品检定研究院 | 2018-07-20 | — | — | CN | disclosed |
| CN-106795199-A | As the nucleoside derivates of 4 ' substitutions of hiv reverse transcriptase inhibitor | 默沙东公司 | 2017-05-31 | — | — | CN | disclosed |