SCHEMBL28148273

SCHEMBL28148273

CC1(C(=O)OCl)CC=CO1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3519679 0.82 MEN1 (0.40) POLBL3MBTL1
SCHEMBL27969550 0.82 POLB (0.33) POLBL3MBTL1
SCHEMBL28191658 0.77 POLB (0.30) POLBL3MBTL1
SCHEMBL18204973 0.77
SCHEMBL28174454 0.77 POLB (0.31) POLBL3MBTL1
Naphthalene SCHEMBL31244560 0.68 HCAR2 (0.37) POLBL3MBTL1
SCHEMBL11007039 0.67
SCHEMBL18789234 0.64 NPSR1 (0.32)
SCHEMBL11640096 0.64 FFAR3 (0.36)
SCHEMBL17916103 0.64 FFAR3 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106999479-A It can be used as the heteroaryl compound of SUMO activating enzyme inhibitors 米伦纽姆医药公司 2017-08-01 CN disclosed