Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.70 |
| ▸ | PPARA | Q07869 | 7/20 | 0.70 |
| ▸ | PPARD | Q03181 | 5/20 | 0.70 |
| ▸ | F7 | P08709 | 5/20 | 0.70 |
| ▸ | F3 | P13726 | 5/20 | 0.70 |
| ▸ | TERT | O14746 | 3/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | FABP4 | P15090 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.70 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.70 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068343 | 1.00 | PPARG (0.70) | PPARGPPARAPPARDF7F3 | |
| Lignoceric Acid SCHEMBL27347357 | 1.00 | PPARG (0.70) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL28829485 | 0.97 | PPARG (0.70) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL5970525 | 0.95 | PPARG (0.61) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL2242535 | 0.95 | PPARG (0.61) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL2242536 | 0.95 | PPARG (0.61) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL5342794 | 0.95 | PPARG (0.61) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL5342783 | 0.95 | PPARG (0.61) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL9388196 | 0.95 | PPARG (0.61) | PPARGPPARAPPARDF7F3 | |
| SCHEMBL5798202 | 0.95 | PPARG (0.61) | PPARGPPARAPPARDF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375898-A | Dosage regimen for Echinocandin compound | 奇达拉治疗公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-104507309-B | Dosing regimen for echinocandin class compounds | 奇达拉治疗公司 | 2017-05-03 | — | — | CN | disclosed |