Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.65 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 2/20 | 0.65 |
| ▸ | FYN | P06241 | 2/20 | 0.65 |
| ▸ | HCK | P08631 | 2/20 | 0.65 |
| ▸ | SRC | P12931 | 2/20 | 0.65 |
| ▸ | JAK3 | P52333 | 2/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.65 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | YES1 | P07947 | 1/20 | 0.59 |
| ▸ | LYN | P07948 | 1/20 | 0.59 |
| ▸ | FGR | P09769 | 1/20 | 0.59 |
| ▸ | KIT | P10721 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148955 | 0.87 | LCK (0.67) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28147823 | 0.85 | LCK (0.64) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL2774894 | 0.83 | LCK (0.83) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL774358 | 0.82 | LCK (0.68) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL16785698 | 0.81 | LCK (0.67) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL773593 | 0.81 | LCK (1.00) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL774486 | 0.81 | MAPK14 (0.77) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28844469 | 0.80 | LCK (0.85) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL774144 | 0.80 | LCK (0.78) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28147824 | 0.80 | LCK (0.85) | LCKMAPK14MAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674150-A | Dasatinib derivative with anti-tumor activity and application thereof | 上海应用技术大学 | 2017-05-17 | — | — | CN | disclosed |