SCHEMBL28150384

SCHEMBL28150384

C=CC(=O)OC(C)O[Si](C)(CCCCCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.37
HPGD P15428 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
MAPT P10636 1/20 0.34
LMNA P02545 3/20 0.33
THRB P10828 2/20 0.33
THRA P10827 1/20 0.33
FAAH O00519 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27985882 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL27985890 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL27985891 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL27985546 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL28229093 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL27985542 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL27985915 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL27985541 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL27985883 1.00 TSHR (0.37) TSHRHPGDZDHHC20ZDHHC2MAPT
SCHEMBL28161660 0.99 TSHR (0.38) TSHRHPGDZDHHC20ZDHHC2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795275-B Actinic-radiation curable composition 株式会社钟化 2019-03-05 CN disclosed
CN-106795275-A Actinic-radiation curable composition 株式会社钟化 2017-05-31 CN disclosed