Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105390 | 0.83 | — | — | |
| SCHEMBL28153080 | 0.80 | TSHR (0.46) | TSHRALDH1A1TDP1NLRP3 | |
| SCHEMBL28152195 | 0.77 | TSHR (0.44) | TSHRCYP1A2MAPK1SLC1A2ALDH1A1 | |
| SCHEMBL28154225 | 0.76 | TSHR (0.70) | TSHRALDH1A1TDP1NLRP3 | |
| SCHEMBL28141086 | 0.76 | TSHR (0.32) | TSHRCYP1A2MAPK1ALDH1A1 | |
| SCHEMBL28813789 | 0.75 | TSHR (0.59) | TSHRCYP1A2MAPK1SLC1A2ALDH1A1 | |
| SCHEMBL28157163 | 0.74 | TSHR (0.59) | TSHRALDH1A1TDP1NLRP3 | |
| SCHEMBL25280163 | 0.73 | — | — | |
| SCHEMBL27872970 | 0.73 | SLC1A2 (0.47) | TSHRCYP1A2MAPK1SLC1A2ALDH1A1 | |
| SCHEMBL28157152 | 0.73 | TSHR (0.56) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106748988-B | A kind of method that supercritical ultrasonics technology synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-05-28 | — | — | CN | claimed |
| CN-106866515-B | A kind of sulfonyl pyridine derivative and its synthetic method | 山东师范大学 | 2019-05-28 | — | — | CN | claimed |
| CN-106866514-B | A kind of method that Aqueous phase synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-05-28 | — | — | CN | claimed |
| CN-106866515-A | A kind of sulfonyl pyridine derivative and its synthetic method | 山东师范大学 | 2017-06-20 | — | — | CN | claimed |
| CN-106866514-A | A kind of method of the Aqueous phase synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate | 山东师范大学 | 2017-06-20 | — | — | CN | claimed |
| CN-106831551-A | A kind of method of the ionic liquid method synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate | 山东师范大学 | 2017-06-13 | — | — | CN | claimed |
| CN-106748988-A | A kind of method of the supercritical ultrasonics technology synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate | 山东师范大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106831551-B | A kind of method that ionic liquid method synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-09-24 | — | — | CN | disclosed |
| CN-106866514-B | A kind of method that Aqueous phase synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate | 山东师范大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-106866515-B | A kind of sulfonyl pyridine derivative and its synthetic method | 山东师范大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-106866515-A | A kind of sulfonyl pyridine derivative and its synthetic method | 山东师范大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-106866514-A | A kind of method of the Aqueous phase synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate | 山东师范大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-106831551-A | A kind of method of the ionic liquid method synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate | 山东师范大学 | 2017-06-13 | — | — | CN | disclosed |