Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223045 | 1.00 | ACE (0.43) | ACECNR1CNR2RENLMNA | |
| SCHEMBL2223050 | 1.00 | ACE (0.43) | ACECNR1CNR2RENLMNA | |
| SCHEMBL28152132 | 1.00 | ACE (0.43) | ACECNR1CNR2RENLMNA | |
| SCHEMBL9107688 | 0.96 | ACE (0.41) | ACECNR1CNR2REN | |
| SCHEMBL1952767 | 0.96 | ACE (0.41) | ACECNR1CNR2REN | |
| SCHEMBL3720680 | 0.94 | CNR2 (0.40) | ACECNR1CNR2 | |
| SCHEMBL3180764 | 0.94 | CNR2 (0.40) | ACECNR1CNR2 | |
| SCHEMBL4336856 | 0.94 | CNR1 (0.42) | ACECNR1CNR2 | |
| SCHEMBL15665698 | 0.94 | CNR1 (0.42) | ACECNR1CNR2 | |
| SCHEMBL3720683 | 0.94 | CNR2 (0.40) | ACECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928126-B | Amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-106928126-A | A kind of amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |