⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777753 | 0.86 | NPSR1 (0.37) | — | |
| SCHEMBL780031 | 0.83 | NPSR1 (0.36) | — | |
| SCHEMBL883061 | 0.74 | — | — | |
| SCHEMBL23145649 | 0.73 | — | — | |
| SCHEMBL50965 | 0.72 | — | — | |
| SCHEMBL24612823 | 0.72 | — | — | |
| SCHEMBL393019 | 0.72 | — | — | |
| SCHEMBL23173366 | 0.69 | — | — | |
| SCHEMBL24174452 | 0.69 | — | — | |
| SCHEMBL12786570 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365511-A1 | Antiviral Pyrazolopiridinone Compounds | NOVARTIS AG (CH) | 2023-11-16 | — | — | US | disclosed |
| US-20230365511-A1 | Antiviral Pyrazolopiridinone Compounds | NOVARTIS AG (CH) | 2023-11-16 | — | — | US | disclosed |
| WO-2021061898-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | NOVARTIS AG (CH) | 2021-04-01 | — | — | WO | disclosed |
| WO-2010115981-A1 | 7-AZADISPIRO [3.0.4.1] DECANE-8-CARBOXAMIDES AS HEPATITIS C VIRUS INHIBITORS | NOVARTIS AG (CH) | 2010-10-14 | — | — | WO | disclosed |