SCHEMBL28158249

SCHEMBL28158249

C[C@H](N)c1cccc(P(c2ccccc2)c2ccccc2)c1P(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP1A2 P05177 1/20 0.38
NFKB1 P19838 1/20 0.38
PNMT P11086 1/20 0.38
LMNA P02545 2/20 0.37
ALDH1A1 P00352 2/20 0.37
GLA P06280 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SLC6A2 P23975 2/20 0.33
TAAR1 Q96RJ0 2/20 0.33
MAOA P21397 2/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
ADRA2A P08913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16292891 0.85 CYP3A4 (0.42) DRD1CYP3A4CYP2D6CYP1A2NFKB1
SCHEMBL668759 0.85 CYP3A4 (0.42) DRD1CYP3A4CYP2D6CYP1A2NFKB1
SCHEMBL29053288 0.85 CYP3A4 (0.42) DRD1CYP3A4CYP2D6CYP1A2NFKB1
SCHEMBL28765143 0.77 CYP3A4 (0.55) DRD1CYP3A4TDP1KDM4EESR1
SCHEMBL23581097 0.74 CYP3A4 (0.46) DRD1CYP3A4TDP1KDM4EESR1
SCHEMBL10024962 0.74 CYP3A4 (0.46) DRD1CYP3A4CYP1A2LMNATDP1
SCHEMBL2846076 0.74 CYP3A4 (0.46) DRD1CYP3A4TDP1KDM4EESR1
SCHEMBL28141110 0.74 CYP3A4 (0.46) DRD1CYP3A4CYP1A2LMNATDP1
SCHEMBL20873230 0.72 TDP1 (0.44) DRD1CYP3A4CYP1A2ALDH1A1TDP1
SCHEMBL7089620 0.71 CYP3A4 (0.42) DRD1CYP3A4CYP1A2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104831296-B A kind of metal pickling corrosion inhibitor, its preparation and application 四川理工学院 2017-09-15 CN disclosed