Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 14/20 | 0.60 |
| ▸ | HTR2B | P41595 | 13/20 | 0.60 |
| ▸ | HTR2A | P28223 | 11/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875115 | 0.85 | CYP3A4 (0.49) | HTR2CHTR2BHTR2ACYP3A4 | |
| SCHEMBL183797 | 0.75 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL18550192 | 0.74 | CYP3A4 (0.52) | HTR2CHTR2BHTR2ACYP3A4 | |
| SCHEMBL300642 | 0.73 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL183534 | 0.72 | HTR2C (0.98) | HTR2CHTR2BHTR2A | |
| SCHEMBL30358618 | 0.72 | CYP3A4 (1.00) | HTR2CHTR2BHTR2ACYP3A4 | |
| SCHEMBL183657 | 0.71 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL183604 | 0.70 | HTR2A (0.81) | HTR2CHTR2BHTR2A | |
| SCHEMBL300930 | 0.69 | HTR2A (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL183656 | 0.69 | HTR2C (1.00) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207532-B | Nitroimidazole derivatives against tuberculosis | 南京明德新药研发股份有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-106946909-A | The nitro imidazole derivatives for the treatment of pulmonery tuberculosis disease | 南京明德新药研发股份有限公司 | 2017-07-14 | — | — | CN | disclosed |