Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.46 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335791 | 0.93 | BRD4 (0.43) | BTKBRD4ATAD2 | |
| SCHEMBL28164541 | 0.93 | BRD4 (0.43) | BTKBRD4ATAD2 | |
| SCHEMBL28165044 | 0.93 | BRD4 (0.43) | BTKBRD4ATAD2 | |
| SCHEMBL28337962 | 0.80 | BTK (0.48) | BTKBRD4ATAD2 | |
| SCHEMBL28335872 | 0.78 | BTK (0.37) | BTKBRD4ATAD2 | |
| SCHEMBL17699525 | 0.78 | BTK (0.69) | BTK | |
| SCHEMBL29782505 | 0.78 | BTK (0.69) | BTK | |
| SCHEMBL28165101 | 0.77 | BTK (0.40) | BTK | |
| SCHEMBL19035389 | 0.76 | BTK (0.44) | BTKBRD4ATAD2EGFR | |
| SCHEMBL28165078 | 0.74 | BTK (0.44) | BTKBRD4ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-A | It can be used as the indole carboxamides compound of kinase inhibitor | BRISTOL MYERS SQUIBB CO | 2019-11-29 | — | — | CN | disclosed |
| CN-107108583-A | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2017-08-29 | — | — | CN | disclosed |