Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737220 | 0.79 | HRH3 (0.38) | HRH3KCNH2PGR | |
| SCHEMBL2737213 | 0.79 | HRH3 (0.38) | HRH3KCNH2PGR | |
| SCHEMBL12205472 | 0.79 | HRH3 (0.38) | HRH3KCNH2PGR | |
| SCHEMBL18068287 | 0.76 | HRH3 (0.36) | HRH3KCNH2PGR | |
| SCHEMBL22007196 | 0.76 | HRH3 (0.36) | HRH3KCNH2PGR | |
| SCHEMBL12386638 | 0.76 | HRH3 (0.36) | HRH3KCNH2PGR | |
| SCHEMBL18347918 | 0.76 | HRH3 (0.36) | HRH3KCNH2PGR | |
| SCHEMBL20676134 | 0.76 | HRH3 (0.36) | HRH3KCNH2PGR | |
| SCHEMBL17067977 | 0.76 | HRH3 (0.36) | HRH3KCNH2PGR | |
| SCHEMBL12259239 | 0.74 | HRH3 (0.47) | HRH3KCNH2BRD4TAF1CECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817549-B | Evil azole compounds with antifungal activity and its preparation method and application | 河南师范大学 | 2017-08-11 | — | — | CN | disclosed |