Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22229902 | 0.81 | ELANE (0.41) | HCRTR1HCRTR2POLBELANELMNA | |
| SCHEMBL26984918 | 0.72 | HTT (0.48) | KDM4EHSD17B10ALDH1A1KMT2ANPC1 | |
| SCHEMBL26984378 | 0.72 | HTT (0.48) | KDM4EHSD17B10ALDH1A1KMT2ANPC1 | |
| SCHEMBL353753 | 0.72 | PLK1 (0.38) | POLBKDM4EGAA | |
| SCHEMBL423518 | 0.69 | GAA (0.35) | POLBKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL30913126 | 0.69 | HTT (0.57) | LMNAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL13366302 | 0.66 | ELANE (0.45) | POLBELANEKDM4EHSD17B10MEN1 | |
| SCHEMBL5724162 | 0.66 | IRAK4 (0.42) | LMNATHRB | |
| SCHEMBL27413269 | 0.65 | SLC29A1 (0.40) | POLBELANELMNAPPARGKDM4E | |
| SCHEMBL26984496 | 0.64 | KMT2A (0.41) | POLBLMNAKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817549-B | Evil azole compounds with antifungal activity and its preparation method and application | 河南师范大学 | 2017-08-11 | — | — | CN | disclosed |