Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 10/20 | 0.59 |
| ▸ | CHUK | O15111 | 9/20 | 0.59 |
| ▸ | CDK11B | P21127 | 2/20 | 0.48 |
| ▸ | CDK7 | P50613 | 2/20 | 0.48 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.48 |
| ▸ | MAP3K19 | Q56UN5 | 2/20 | 0.48 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.48 |
| ▸ | CDK11A | Q9UQ88 | 2/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.48 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819995 | 0.92 | IKBKB (0.54) | IKBKBCHUKCDK11BCDK7CDK13 | |
| SCHEMBL2813901 | 0.89 | IKBKB (0.51) | IKBKBCHUKCDK11BCDK7CDK13 | |
| SCHEMBL2813904 | 0.85 | PDE2A (0.49) | IKBKBCHUKPDE2APDE10ATP53 | |
| SCHEMBL2814028 | 0.84 | IKBKB (0.48) | IKBKBCHUKCDK11BCDK7CDK13 | |
| SCHEMBL2815341 | 0.83 | IKBKB (0.56) | IKBKBCHUKCDK11BCDK7CDK13 | |
| SCHEMBL2816653 | 0.81 | IKBKB (0.46) | IKBKBCHUKCDK11BCDK7CDK13 | |
| SCHEMBL2814867 | 0.81 | IKBKB (0.61) | IKBKBCHUKCDK11BCDK7CDK13 | |
| SCHEMBL2819611 | 0.80 | ADORA2A (0.55) | PDE2APDE10ATP53ALDH1A1NPSR1 | |
| SCHEMBL2819760 | 0.80 | IKBKB (0.48) | IKBKBCHUKCDK11BCDK7CDK13 | |
| SCHEMBL2816313 | 0.79 | IKBKB (0.48) | IKBKBCHUKCDK11BCDK7CDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205602-B1 | IMIDAZO[1,2-A]QUINOXALINES AND DERIVATIVES THEREOF FOR TREATING CANCERS | UNIV MONTPELLIER (FR) | 2018-09-26 | — | — | EP | claimed |
| US-8378098-B2 | Imidazol[1,2-α]quinoxalines and derivatives for the treatment of cancers | UNIVERSITE DE MONTPELLIER I (FR) | 2013-02-19 | — | — | US | claimed |
| US-20100249142-A1 | IMIDAZOL[1,2-alpha]QUINOXALINES AND DERIVATIVES FOR THE TREATMENT OF CANCERS | UNIVERSITE DE MONTPELLIER I | 2010-09-30 | — | — | US | claimed |
| US-8378098-B2 | Imidazol[1,2-α]quinoxalines and derivatives for the treatment of cancers | UNIVERSITE DE MONTPELLIER I (FR) | 2013-02-19 | — | — | US | disclosed |
| US-20100249142-A1 | IMIDAZOL[1,2-alpha]QUINOXALINES AND DERIVATIVES FOR THE TREATMENT OF CANCERS | UNIVERSITE DE MONTPELLIER I | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249142-A1 | IMIDAZOL[1,2-alpha]QUINOXALINES AND DERIVATIVES FOR THE TREATMENT OF CANCERS | IDH3A, NRAS, KRAS | IKBKB 855/4885CHUK 409/4885CDK11B 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.