Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28085052 | 0.90 | SNCA (0.50) | SNCAHIF1ATRPA1TP53TAAR1 | |
| Bromide SCHEMBL8331435 | 0.89 | SNCA (0.64) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL494 | 0.87 | SNCA (0.63) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Bromide SCHEMBL163158 | 0.87 | SNCA (0.67) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28828301 | 0.85 | SNCA (0.61) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Hydrogen Sulfide SCHEMBL28069220 | 0.85 | SNCA (0.61) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Arsenic SCHEMBL27730172 | 0.85 | SNCA (0.61) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Methane SCHEMBL28097927 | 0.85 | SNCA (0.61) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Phosphine SCHEMBL27546596 | 0.85 | SNCA (0.61) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27987350 | 0.85 | SNCA (0.61) | SNCAHIF1ATAAR1SLC6A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183809-B | Epoxy resin composition for transparent circuit board and laminated glass sheet | 日本化药株式会社 | 2017-09-29 | — | — | CN | disclosed |
| CN-107207641-A | Composition for forming cured film, alignment material, and phase difference material | 日产化学工业株式会社 | 2017-09-26 | — | — | CN | disclosed |