Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007433 | 0.87 | MAPT (0.62) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28723007 | 0.82 | MEN1 (0.82) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL12503662 | 0.81 | GSK3B (0.53) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL16817686 | 0.80 | MAPT (0.57) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6769441 | 0.80 | MAPT (0.68) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL23728052 | 0.80 | GSK3B (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL4929277 | 0.79 | MEN1 (0.77) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL10940028 | 0.78 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL10942052 | 0.78 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8879368 | 0.77 | MAPT (0.80) | MAPTMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395324-B | Mi Zuo Bing oxadiazoles and imidazo thiadiazoles derivative | 阿瑞斯贸易股份有限公司 | 2017-09-12 | — | — | CN | disclosed |