Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495989 | 0.88 | EPHX1 (0.49) | EPHX1TDP1KMT2AMEN1GAA | |
| SCHEMBL15778776 | 0.84 | EPHX1 (0.41) | EPHX1TDP1CTSSCTSKKMT2A | |
| SCHEMBL13744596 | 0.83 | EPHX1 (0.45) | EPHX1TDP1KMT2AMEN1GAA | |
| SCHEMBL24951947 | 0.83 | EPHX1 (0.54) | EPHX1TDP1CTSSCTSKKMT2A | |
| Bicarbonate SCHEMBL5548474 | 0.82 | EPHX1 (0.44) | EPHX1TDP1CTSSCTSKKMT2A | |
| SCHEMBL6896596 | 0.81 | EPHX1 (0.56) | EPHX1TDP1CTSSCTSKKMT2A | |
| SCHEMBL28036497 | 0.81 | EPHX1 (0.39) | EPHX1TDP1CTSSCTSKKMT2A | |
| SCHEMBL15777686 | 0.80 | KMT2A (0.39) | EPHX1TDP1CTSSCTSKKMT2A | |
| SCHEMBL21244678 | 0.80 | EPHX1 (0.42) | EPHX1TDP1CTSKKMT2AMEN1 | |
| SCHEMBL4622655 | 0.79 | EPHX1 (0.44) | EPHX1TDP1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026407-B | Beta-lactamase inhibitors | 维纳拓尔斯制药公司 | 2017-09-08 | — | — | CN | disclosed |