Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415610 | 0.79 | DAO (0.57) | DAODDOFLT3AOC3KDM4E | |
| SCHEMBL186718 | 0.79 | DAO (0.57) | DAODDOFLT3AOC3KDM4E | |
| 2-Phenyl-1H-Indole SCHEMBL29008225 | 0.79 | NPC1 (0.65) | KDM4EMAPTHPGDNPC1RAB9A | |
| Piperazine SCHEMBL28221461 | 0.78 | HRH4 (0.49) | DAODDOFLT3AOC3KDM4E | |
| Naphthalene SCHEMBL27543353 | 0.77 | CYP2A6 (0.38) | KDM4EMAPTCYP2A6ALDH1A1LMNA | |
| Methane SCHEMBL28880843 | 0.77 | DAO (0.55) | DAODDOFLT3AOC3KDM4E | |
| Fluoride SCHEMBL27618960 | 0.77 | DAO (0.55) | DAODDOFLT3AOC3KDM4E | |
| Hydrochloric Acid SCHEMBL9638778 | 0.77 | AOC3 (0.56) | DAODDOFLT3AOC3KDM4E | |
| Hydrochloric Acid SCHEMBL29788370 | 0.77 | AOC3 (0.56) | DAODDOFLT3AOC3KDM4E | |
| SCHEMBL27660600 | 0.77 | DAO (0.55) | DAODDOFLT3AOC3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105131014-B | A kind of loop coil hydroxyindole imidazoline and oxygen azatropylidene compound and its synthetic method | 苏州大学张家港工业技术研究院 | 2017-09-05 | — | — | CN | claimed |
| CN-105131014-B | A kind of loop coil hydroxyindole imidazoline and oxygen azatropylidene compound and its synthetic method | 苏州大学张家港工业技术研究院 | 2017-09-05 | — | — | CN | disclosed |
| CN-105131014-B | A kind of loop coil hydroxyindole imidazoline and oxygen azatropylidene compound and its synthetic method | 苏州大学张家港工业技术研究院 | 2017-09-05 | — | — | CN | disclosed |
| CN-105131014-B | A kind of loop coil hydroxyindole imidazoline and oxygen azatropylidene compound and its synthetic method | 苏州大学张家港工业技术研究院 | 2017-09-05 | — | — | CN | disclosed |