Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 4/20 | 0.33 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL28084557 | 0.96 | CA4 (0.44) | CA1CA4TSHRFFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28094807 | 0.96 | CA1 (0.47) | CA1CA4TSHRFFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL108420 | 0.96 | — | — | |
| Tetramethylammonium Ion SCHEMBL22076673 | 0.92 | CA1 (0.43) | CA1CA4TSHRFFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28601218 | 0.92 | CA1 (0.43) | CA1CA4TSHRFFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28027866 | 0.92 | CA1 (0.43) | CA1CA4TSHRFFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL9748331 | 0.88 | CA1 (0.40) | CA1CA4TSHRFFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28127941 | 0.88 | CA1 (0.40) | CA1CA4TSHRFFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28607016 | 0.87 | CA1 (0.46) | CA1CA4BBOX1SLC22A16CHRNB2 | |
| Oxalic Acid SCHEMBL1310796 | 0.83 | CA4 (0.54) | CA1CA4BBOX1SLC22A16CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107281994-B | Circulation shell and tube reactor series connection tubular reactor prepares the device and method of tetramethyl ammonium hydrogen carbonate | 天津大学 | 2019-08-27 | — | — | CN | disclosed |
| CN-107281994-A | Circulation shell and tube reactor series connection tubular reactor prepares the device and method of tetramethyl ammonium hydrogen carbonate | 天津大学 | 2017-10-24 | — | — | CN | disclosed |