SCHEMBL28179552

SCHEMBL28179552

CC[C@@]1(Oc2ccc(OCc3ccccc3)cc2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
CYP2C19 P33261 1/20 0.41
PTGS2 P35354 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HIF1A Q16665 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
SLC5A1 P13866 3/20 0.40
SLC5A2 P31639 3/20 0.40
MAOB P27338 2/20 0.39
LTA4H P09960 1/20 0.39
EPHX2 P34913 1/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28227680 0.84 TYR (0.46) PTGS2SLC5A1SLC5A2LTA4HGAA
SCHEMBL28716077 0.80 MAOB (0.49) MAOBEPHX2L3MBTL1RAB9AMAPT
SCHEMBL4574200 0.79 SLC5A2 (0.37) SLC5A1SLC5A2
SCHEMBL29212932 0.78 SLC5A2 (0.38) SLC5A1SLC5A2
SCHEMBL10351758 0.71 CDK1 (0.40) SLC6A2CYP2C19SLC5A2
SCHEMBL15298186 0.70 SLC5A2 (0.56) SLC5A1SLC5A2
SCHEMBL28915008 0.70 TSHR (0.36) SLC6A2CYP2C19SLC5A2GAA
SCHEMBL7694159 0.69 TYR (0.68) SLC5A1SLC5A2
SCHEMBL9745158 0.69 PDE4D (0.39) SLC6A2
SCHEMBL9745489 0.69 PDE4D (0.39) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592321-B The process for catalytic synthesis of rhodioside 武汉信嘉和诚药物化学有限公司 2017-09-19 CN disclosed