Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181100 | 0.91 | APP (0.68) | APPATML3MBTL1DRD4DRD2 | |
| SCHEMBL17465617 | 0.89 | ATM (0.58) | ATML3MBTL1NOS1DRD4DRD2 | |
| SCHEMBL7898603 | 0.89 | ATM (0.58) | ATML3MBTL1NOS1DRD4DRD2 | |
| SCHEMBL17445905 | 0.87 | ATM (0.60) | APPATML3MBTL1NOS1DRD4 | |
| SCHEMBL11563384 | 0.83 | ATM (0.50) | APPATML3MBTL1NOS1DRD4 | |
| SCHEMBL21114104 | 0.83 | APP (0.47) | APPDRD3 | |
| SCHEMBL13472002 | 0.83 | ATM (0.50) | APPATML3MBTL1NOS1DRD4 | |
| SCHEMBL18235025 | 0.82 | DRD4 (0.57) | APPATML3MBTL1NOS1DRD4 | |
| SCHEMBL6132633 | 0.81 | ATM (0.51) | ATML3MBTL1NOS1DRD4DRD2 | |
| SCHEMBL8393205 | 0.81 | APP (0.48) | APPDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107353209-B | There are the two phenoxy group flexible molecules and its preparation method and application of high-affinity with A β plaque block | 北京师范大学 | 2019-07-19 | — | — | CN | disclosed |
| CN-107353209-A | There are two phenoxy group flexible molecules of high-affinity and its preparation method and application with A β plaque block | 北京师范大学 | 2017-11-17 | — | — | CN | disclosed |