Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181504 | 1.00 | MAPT (0.49) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL28619015 | 0.90 | MAPT (0.49) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL28619014 | 0.90 | MAPT (0.49) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL28606573 | 0.85 | MAPT (0.54) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL28606575 | 0.85 | MAPT (0.54) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL28180768 | 0.85 | GAA (0.52) | MAPTALDH1A1HTTGAAKMT2A | |
| SCHEMBL28180767 | 0.85 | GAA (0.52) | MAPTALDH1A1HTTGAAKMT2A | |
| SCHEMBL28615007 | 0.85 | KMT2A (0.48) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL28606655 | 0.85 | MAPT (0.46) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL28606656 | 0.85 | MAPT (0.46) | MAPTALDH1A1HTTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107188771-B | Chiral synthesis method of gamma-nitrophenol compound | 浙江工业大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-107188771-A | Chiral synthesis method of gamma-nitrophenol compound | 浙江工业大学 | 2017-09-22 | — | — | CN | disclosed |