Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | HTR2B | P41595 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20456469 | 0.86 | HTR2B (0.86) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL20456414 | 0.86 | KMT2A (0.78) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL20456209 | 0.84 | KMT2A (1.00) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL1299053 | 0.84 | HTR2B (1.00) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL20456427 | 0.81 | KMT2A (0.74) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL20456208 | 0.81 | KMT2A (0.74) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL20456451 | 0.81 | KMT2A (0.78) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL20456447 | 0.81 | HTR2B (0.78) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL25232120 | 0.81 | KMT2A (0.64) | KMT2AHTR2BMAPTALDH1A1LMNA | |
| SCHEMBL30456888 | 0.81 | KMT2A (0.64) | KMT2AHTR2BMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860919-B | Benzimidizole derivatives containing piperidines and its production and use | 天津药物研究院有限公司 | 2017-11-10 | — | — | CN | disclosed |