Formaldehyde

Formaldehyde

SCHEMBL28181539

C=O.CCOC(=O)CC(C)=O.CCOC(=O)CC(C)=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.67
MGAM O43451 2/20 0.67
SI P14410 2/20 0.67
MGAM2 Q2M2H8 2/20 0.67
ALDH1A1 P00352 4/20 0.48
TRPA1 O75762 1/20 0.48
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CYP1A2 P05177 1/20 0.41
ALOX15 P16050 2/20 0.40
SOAT1 P35610 1/20 0.40
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
MAPT P10636 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28376088 0.98 GAA (0.64) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28208665 0.95 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1
Ethylene SCHEMBL28264916 0.95 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1331371 0.95
SCHEMBL1332259 0.95
SCHEMBL1330988 0.95
SCHEMBL1871576 0.95 GAA (0.74) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1331762 0.95
SCHEMBL1331782 0.95
SCHEMBL15500 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107188856-A The synthetic method of the methylpyrimidine of 2 amino, 4 hydroxyl 6 宁夏医科大学 2017-09-22 CN disclosed