Benzene

Benzene

SCHEMBL28186125

CCN=C=S.c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MIF P14174 10/20 0.44
TRPA1 O75762 6/20 0.44
CYP3A4 P08684 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
CYP2E1 P05181 1/20 0.41
CYP2A6 P11509 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP2A13 Q16696 1/20 0.41
EPAS1 Q99814 1/20 0.41
NAAA Q02083 5/20 0.40
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
TSHR P16473 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Isothiocyanate SCHEMBL287524 0.90
Ethyl Isothiocyanate SCHEMBL11120171 0.87
Ethyl Isothiocyanate SCHEMBL27916476 0.87
Biphenyl SCHEMBL17835321 0.85 MIF (0.50) MIFTRPA1CYP3A4ALDH1A1HPGD
Toluene SCHEMBL29140425 0.83 MIF (0.48) MIFTRPA1CYP3A4ALDH1A1HPGD
Ethyl Isothiocyanate SCHEMBL1811949 0.82
Chlorobenzene SCHEMBL28864453 0.82 MIF (0.47) MIFTRPA1CYP3A4ALDH1A1HPGD
Ethyl Isothiocyanate SCHEMBL25213788 0.81
Ethyl Isothiocyanate SCHEMBL28386540 0.81
Ethyl Isothiocyanate SCHEMBL8698367 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107412076-A A kind of antiperspirant and its application 广州聚注通用技术研究院有限公司 2017-12-01 CN disclosed