(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL28186405

C(=Cc1ccccc1)c1ccccc1.N.S

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.65
NFE2L2 Q16236 4/20 0.60
CYP19A1 P11511 2/20 0.60
MAOA P21397 2/20 0.60
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
CHAT P28329 2/20 0.55
TRPA1 O75762 3/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.52
ALOX5 P09917 1/20 0.52
MAPK1 P28482 1/20 0.52
RELA Q04206 2/20 0.52
CYP11B1 P15538 1/20 0.52
CYP11B2 P19099 1/20 0.52
KDM4E B2RXH2 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL27570209 0.96 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL819152 0.96 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL1282295 0.96 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL11573776 0.96 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL28508146 0.96 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL27480001 0.96 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL1376696 0.96 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL443 0.93 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.93 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.93 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104434935-B Dense therapeutic phospholipid composition 阿卡斯蒂制药股份有限公司 2019-07-16 CN disclosed
CN-107529753-A The synthesis of circular muscle acid and the like 卢莫斯制药公司 2018-01-02 CN disclosed
CN-107427494-A The micro- supensoid agent of circular muscle acid 卢莫斯制药公司 2017-12-01 CN disclosed