Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189029 | 1.00 | KDM1A (1.00) | KDM1ACYP19A1MAOAMAOBNPC1 | |
| SCHEMBL4919409 | 0.81 | KDM1A (0.70) | KDM1ANPC1MAPT | |
| SCHEMBL6797387 | 0.75 | CYP19A1 (0.63) | KDM1ACYP19A1MAOAMAOBNPC1 | |
| SCHEMBL6797384 | 0.75 | CYP19A1 (0.63) | KDM1ACYP19A1MAOAMAOBNPC1 | |
| SCHEMBL5687683 | 0.73 | KDM1A (0.59) | KDM1ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL5687735 | 0.71 | KDM1A (0.57) | KDM1ANPC1MAPT | |
| SCHEMBL11288404 | 0.70 | CYP19A1 (0.91) | KDM1ACYP19A1MAOAMAOBNPC1 | |
| SCHEMBL11288405 | 0.70 | CYP19A1 (0.91) | KDM1ACYP19A1MAOAMAOBNPC1 | |
| SCHEMBL2774532 | 0.70 | CYP19A1 (0.86) | KDM1ACYP19A1MAOAMAOBNPC1 | |
| SCHEMBL29664559 | 0.70 | CYP19A1 (0.86) | KDM1ACYP19A1MAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501169-A | A kind of trans diarylethene LSD1 inhibitor, its preparation method and application | 新乡医学院 | 2017-12-22 | — | — | CN | disclosed |