Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075718 | 0.86 | OPRL1 (0.46) | OPRL1CYP2C9ABCB1ALDH1A1LMNA | |
| SCHEMBL17075722 | 0.86 | OPRL1 (0.46) | OPRL1CYP2C9ABCB1ALDH1A1LMNA | |
| SCHEMBL17075724 | 0.86 | OPRL1 (0.46) | OPRL1CYP2C9ABCB1ALDH1A1LMNA | |
| SCHEMBL14128674 | 0.85 | ABCB1 (0.47) | OPRL1ABCB1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL4818957 | 0.80 | OPRL1 (0.41) | OPRL1CYP2C9ABCB1ALDH1A1LMNA | |
| SCHEMBL9248387 | 0.79 | OPRL1 (0.46) | OPRL1CYP2C9ABCB1MAPTMEN1 | |
| SCHEMBL9248396 | 0.79 | OPRL1 (0.46) | OPRL1CYP2C9ABCB1MAPTMEN1 | |
| SCHEMBL4650914 | 0.79 | OPRL1 (0.41) | OPRL1CYP2C9ABCB1ALDH1A1LMNA | |
| SCHEMBL28483699 | 0.76 | OPRL1 (0.45) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL716244 | 0.76 | OPRL1 (0.45) | OPRL1CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107541220-B | A kind of liquid-crystal compounds and the preparation method and application thereof | 北京八亿时空液晶科技股份有限公司 | 2019-02-15 | — | — | CN | disclosed |
| CN-107541220-A | A kind of liquid-crystal compounds and preparation method and application | 北京八亿时空液晶科技股份有限公司 | 2018-01-05 | — | — | CN | disclosed |