Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.58 |
| ▸ | CCR5 | P51681 | 3/20 | 0.58 |
| ▸ | CCR8 | P51685 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.58 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698104 | 0.96 | MEN1 (0.56) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL19275982 | 0.91 | SMN1; SMN2 (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL17394810 | 0.88 | SMN1; SMN2 (0.53) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12579261 | 0.88 | MEN1 (0.61) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19882073 | 0.88 | KDM4E (0.63) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12210970 | 0.88 | MEN1 (0.61) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29429006 | 0.88 | SMN1; SMN2 (0.53) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12210844 | 0.88 | MEN1 (0.61) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10051455 | 0.88 | MEN1 (0.61) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23161819 | 0.88 | MEN1 (0.53) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445943-A | One kind uses the phenyl 4,6 2 of solid-state reaction under microwave 2（2 pyridines）The method of pyrimidine | 河南科技大学 | 2017-12-08 | — | — | CN | disclosed |