Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800460 | 0.86 | HPGD (0.54) | KMT2ATTRTAAR1MEN1HPGD | |
| SCHEMBL29431297 | 0.79 | HSD17B10 (0.61) | KMT2ATTRTAAR1MEN1NPC1 | |
| SCHEMBL155982 | 0.79 | HSD17B10 (0.61) | KMT2ATTRTAAR1MEN1NPC1 | |
| 1,2-Dimethoxybenzene SCHEMBL27707733 | 0.79 | KMT2A (0.69) | KMT2AHPGDHTTPOLBTSHR | |
| Hydrochloric Acid SCHEMBL2527513 | 0.78 | HSD17B10 (0.59) | KMT2ATTRTAAR1MEN1NPC1 | |
| SCHEMBL28215186 | 0.78 | HSD17B10 (0.59) | KMT2ATTRTAAR1MEN1NPC1 | |
| SCHEMBL28118170 | 0.77 | ATM (0.58) | KMT2ATTRTAAR1MEN1HPGD | |
| SCHEMBL1419560 | 0.77 | KMT2A (0.53) | KMT2AMEN1HPGDHTTNPC1 | |
| SCHEMBL7971405 | 0.76 | TAAR1 (0.55) | KMT2ATTRTAAR1MEN1NPC1 | |
| SCHEMBL30040153 | 0.76 | TAAR1 (0.55) | KMT2ATTRTAAR1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107548397-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107548396-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |