SCHEMBL28192593

SCHEMBL28192593

Cc1cnc(S)c(C(N)=O)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.38
SIRT3 Q9NTG7 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NNMT P40261 3/20 0.35
PKMYT1 Q99640 5/20 0.33
CCR1 P32246 1/20 0.32
CCR5 P51681 1/20 0.32
CCR8 P51685 1/20 0.32
NTRK1 P04629 2/20 0.31
PIM1 P11309 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
SIRT6 Q8N6T7 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8828428 0.80 POLB (0.40) POLBSIRT3TDP1NNMTPKMYT1
Hydrochloric Acid SCHEMBL27450439 0.78 POLB (0.39) POLBSIRT3TDP1NNMTPKMYT1
SCHEMBL27448979 0.77 POLB (0.50) POLBSIRT3TDP1NNMTPKMYT1
Formic Acid SCHEMBL28545687 0.74 POLB (0.36) POLBSIRT3TDP1NNMTPKMYT1
SCHEMBL10430661 0.73 POLB (0.35) POLBSIRT3TDP1NNMTPKMYT1
SCHEMBL16652083 0.72 POLB (0.40) POLBSIRT3TDP1NNMTPKMYT1
SCHEMBL16931059 0.72 HSP90AA1 (0.39) POLBSIRT3TDP1NNMTCYP1A2
SCHEMBL22694670 0.71 POLB (0.43) POLBSIRT3TDP1NNMTPKMYT1
SCHEMBL29827533 0.69 PARP1 (0.39) POLBSIRT3TDP1NNMTCCR1
SCHEMBL20555873 0.69 PARP1 (0.39) POLBSIRT3TDP1NNMTCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107411992-A Make the method for keratin material decolouring using thiopyridone compound 莱雅公司 2017-12-01 CN claimed