Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.46 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23731 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL27516621 | 0.80 | — | — | |
| Methylsulfanylmethane SCHEMBL5796241 | 0.78 | MAP3K14 (0.43) | CRBNDDB1MAP3K14NPC1CYP19A1 | |
| Chloroform SCHEMBL28126218 | 0.76 | MAP3K14 (0.44) | CRBNMAP3K14CYP19A1LMNAMAPT | |
| SCHEMBL17043255 | 0.71 | CYP19A1 (0.32) | CYP19A1 | |
| Succinchlorimide SCHEMBL4989226 | 0.68 | MAP3K14 (0.38) | CRBNDDB1MAP3K14CYP19A1 | |
| SCHEMBL28232946 | 0.68 | CYP3A4 (0.41) | CRBNDDB1MAP3K14CYP19A1LMNA | |
| SCHEMBL28194398 | 0.67 | MAP3K14 (0.36) | CRBNDDB1MAP3K14LMNATSHR | |
| SCHEMBL82304 | 0.64 | — | — | |
| SCHEMBL21965809 | 0.64 | DDB1 (1.00) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106434434-B | One plant of strains A rthrobacter woluwensis for producing dimethylbenzene monooxygenase and its application | 迪沙药业集团有限公司 | 2017-12-22 | — | — | CN | disclosed |