SCHEMBL28194397

SCHEMBL28194397

CCCCCC(=O)NS(=O)(=O)O.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.52
FAAH O00519 6/20 0.50
EPHX2 P34913 1/20 0.49
MEN1 O00255 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
CES2 O00748 4/20 0.44
CES1 P23141 4/20 0.44
CASP2 P42575 1/20 0.44
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
AKR1B1 P15121 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
DNM1 Q05193 2/20 0.42
TRPV1 Q8NER1 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180177 0.98 HSP90AA1 (0.54) HSP90AA1FAAHEPHX2MEN1MAPK1
SCHEMBL7185340 0.96 HSP90AA1 (0.57) HSP90AA1FAAHEPHX2MEN1MAPK1
SCHEMBL11649466 0.96 HSP90AA1 (0.57) HSP90AA1FAAHEPHX2MEN1MAPK1
SCHEMBL21060856 0.96 HSP90AA1 (0.57) HSP90AA1FAAHEPHX2MEN1MAPK1
SCHEMBL7184916 0.96 HSP90AA1 (0.57) HSP90AA1FAAHEPHX2MEN1MAPK1
SCHEMBL3477319 0.91 FNTA (0.46) HSP90AA1FAAHEPHX2MEN1MAPK1
SCHEMBL8087887 0.85 HDAC3 (0.48) EPHX2MEN1KMT2ACES2CES1
SCHEMBL177558 0.82 HDAC3 (0.50) EPHX2MEN1KMT2ACES2CES1
SCHEMBL2810388 0.81 EPHX2 (0.62) HSP90AA1FAAHEPHX2MEN1MAPK1
SCHEMBL2807682 0.81 HSP90AA1 (0.54) HSP90AA1FAAHEPHX2MEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107614475-A COMPOUNDS EFFECTIVE IN TREATING HEPATOTOXICITY AND FATTY LIVER DISEASES AND USES THEREOF 欣耀生医股份有限公司 2018-01-19 CN claimed
CN-107614475-A COMPOUNDS EFFECTIVE IN TREATING HEPATOTOXICITY AND FATTY LIVER DISEASES AND USES THEREOF 欣耀生医股份有限公司 2018-01-19 CN disclosed