Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.80 |
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | NPC1 | O15118 | 5/20 | 0.80 |
| ▸ | RAB9A | P51151 | 5/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.80 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.80 |
| ▸ | RELA | Q04206 | 2/20 | 0.80 |
| ▸ | CASP3 | P42574 | 2/20 | 0.80 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.80 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.80 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199295 | 0.86 | MEN1 (0.60) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13492787 | 0.86 | MAPT (0.79) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17199300 | 0.83 | MEN1 (0.56) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1699257 | 0.82 | MAPT (0.55) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1663375 | 0.81 | MAPT (0.56) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28698076 | 0.76 | KMT2A (0.51) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11009835 | 0.76 | MEN1 (0.52) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL654958 | 0.76 | MAPT (0.77) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11010720 | 0.76 | MEN1 (0.53) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27627290 | 0.75 | PPARG (0.63) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602472-A | A kind of preparation method of 2 substitution 2H indazole compounds | 上海应用技术大学 | 2018-01-19 | — | — | CN | disclosed |