Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389346 | 0.81 | ABCG2 (0.60) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL28205132 | 0.79 | CA1 (0.54) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL18079037 | 0.78 | DDR2 (0.60) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL29432613 | 0.77 | DDR2 (0.59) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| Flavonol SCHEMBL28173937 | 0.75 | KDM4E (0.85) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL29349443 | 0.75 | KMT2A (0.69) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL693914 | 0.75 | KMT2A (0.69) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL31319016 | 0.75 | ABCG2 (0.60) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL5178618 | 0.75 | ABCG2 (0.60) | KDM4EKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL8498992 | 0.74 | KDM4E (0.64) | KDM4EKMT2ALMNAMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573313-A | A kind of hydroxypropyl flavone compound in rose waste residue and preparation method and application | 云南中烟工业有限责任公司 | 2018-01-12 | — | — | CN | claimed |
| CN-107573313-A | A kind of hydroxypropyl flavone compound in rose waste residue and preparation method and application | 云南中烟工业有限责任公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-107573313-A | A kind of hydroxypropyl flavone compound in rose waste residue and preparation method and application | 云南中烟工业有限责任公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-107573313-A | A kind of hydroxypropyl flavone compound in rose waste residue and preparation method and application | 云南中烟工业有限责任公司 | 2018-01-12 | — | — | CN | disclosed |