Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2506153 | 0.93 | KMT2A (0.57) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL23639738 | 0.90 | KMT2A (0.72) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL31321630 | 0.90 | KMT2A (0.72) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL17951283 | 0.86 | KMT2A (0.64) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL16610045 | 0.85 | KMT2A (0.71) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2815601 | 0.85 | PPARG (0.53) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL22406315 | 0.85 | KMT2A (0.63) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2502958 | 0.84 | KMT2A (0.54) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL9340141 | 0.84 | KMT2A (0.69) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL4733370 | 0.83 | SERPINE1 (0.55) | KMT2AMEN1CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869822-B2 | Compositions for treatment of dermatological diseases and conditions and methods of use thereof | DermaMedics, LLC (US) | 2020-12-22 | — | — | US | disclosed |
| US-20180235859-A1 | Compositions for Treatment of Dermatological Diseases and Conditions and Methods of Use Thereof | DermaMedics, LLC | 2018-08-23 | — | — | US | disclosed |
| US-9980887-B2 | Compositions for use in treatment of hyperpigmentation and methods of use thereof | DermaMedics, LLC (US) | 2018-05-29 | — | — | US | disclosed |
| EP-3238696-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | Therametics, Llc (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9622950-B2 | Compositions for use in treatment of dermatological diseases and conditions | DermaMedics, LLC (US) | 2017-04-18 | — | — | US | disclosed |
| US-9616006-B2 | Methods and compositions for treating dermatological diseases and conditions | DermaMedics, LLC (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160346180-A1 | Compositions for Use in Treatment of Dermatological Diseases and Conditions and Methods of Use Thereof | DERMAMEDICS LLC (US) | 2016-12-01 | — | — | US | disclosed |
| US-20130289006-A1 | COMPOSITIONS FOR TREATING HYPERPIGMENTATION AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-31 | — | — | US | disclosed |
| US-20130281411-A1 | COMPOSITIONS FOR TREATING INFLAMMATORY DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-24 | — | — | US | disclosed |
| US-20130280195-A1 | COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-24 | — | — | US | disclosed |
| US-20130274231-A1 | COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS | DermaMedics, LLC | 2013-10-17 | — | — | US | disclosed |
| EP-2244690-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | Therametics, Llc (US) | 2010-11-03 | — | — | EP | disclosed |
| US-20100249244-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | THERAMETICS, LLC | 2010-09-30 | — | — | US | disclosed |
| WO-2009049172-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | THERAMETICS, LLC (US) | 2009-04-16 | — | — | WO | disclosed |