Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327097 | 0.86 | HSP90AA1 (0.39) | HSP90AA1ABCB1GCGRBACE1 | |
| SCHEMBL30605076 | 0.81 | ABCB1 (0.39) | HSP90AA1PTGS1ABCB1GCGR | |
| SCHEMBL11326462 | 0.79 | HSP90AA1 (0.39) | HSP90AA1ABCB1GCGRBACE1 | |
| SCHEMBL11313436 | 0.77 | USP7 (0.35) | HSP90AA1PTGS1ABCB1ESR2GCGR | |
| SCHEMBL8761366 | 0.74 | HSP90AA1 (0.41) | HSP90AA1PTGS1ABCB1ESR2BACE1 | |
| SCHEMBL629526 | 0.74 | ABCB1 (0.35) | HSP90AA1ABCB1GCGR | |
| SCHEMBL17924597 | 0.74 | ABCB1 (0.35) | HSP90AA1ABCB1 | |
| SCHEMBL28313775 | 0.74 | CA1 (0.45) | HSP90AA1PTGS1ABCB1 | |
| SCHEMBL8135460 | 0.73 | GCGR (0.35) | HSP90AA1PTGS1ESR2GCGR | |
| SCHEMBL12006507 | 0.72 | HSP90AA1 (0.37) | HSP90AA1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660148-B | Compounds for preventing or treating organ damage | 萨尔法泰克有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-107660148-A | Compounds for preventing or treating organ damage | 萨尔法泰克有限公司 | 2018-02-02 | — | — | CN | disclosed |