Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24930547 | 0.80 | CYP1A2 (0.41) | SLC5A2HTTSMN1; SMN2NOTUMKDM4E | |
| SCHEMBL29141451 | 0.79 | SLC5A2 (0.35) | SLC5A2MAT2AHTTSMN1; SMN2NOTUM | |
| SCHEMBL1637329 | 0.79 | HDAC8 (0.39) | SLC5A2MAT2AHTTSMN1; SMN2NOTUM | |
| SCHEMBL188317 | 0.79 | KDM4E (0.43) | SLC5A2MAT2AHTTSMN1; SMN2KDM4E | |
| SCHEMBL21191965 | 0.79 | NPC1 (0.40) | SLC5A2MAT2AHTTNOTUMKDM4E | |
| SCHEMBL904601 | 0.76 | SLC5A2 (0.41) | SLC5A2MAT2AHTTSMN1; SMN2NOTUM | |
| SCHEMBL904586 | 0.76 | SLC5A2 (0.46) | SLC5A2MAT2AHTTSMN1; SMN2NOTUM | |
| SCHEMBL22020836 | 0.76 | NPC1 (0.38) | SLC5A2MAT2AHTTSMN1; SMN2NOTUM | |
| SCHEMBL906893 | 0.76 | SLC5A2 (0.34) | SLC5A2MAT2AHTTSMN1; SMN2NOTUM | |
| SCHEMBL23498045 | 0.75 | HDAC6 (0.41) | SLC5A2MAT2AHTTSMN1; SMN2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709315-A | The inhibitor of bruton's tyrosine kinase | 药品循环有限责任公司 | 2018-02-16 | — | — | CN | disclosed |