Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.67 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.67 |
| ▸ | CETP | P11597 | 7/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088776 | 0.98 | CYP4F2 (0.69) | CYP4F2CYP4A11CETPNPSR1MAPT | |
| SCHEMBL2235513 | 0.95 | CYP4F2 (0.70) | CYP4F2CYP4A11CETPNPSR1MAPT | |
| SCHEMBL4944314 | 0.94 | CYP4F2 (0.64) | CYP4F2CYP4A11CETPNPSR1MEN1 | |
| SCHEMBL3150942 | 0.93 | CYP4F2 (0.72) | CYP4F2CYP4A11CETPNPSR1MEN1 | |
| SCHEMBL5052685 | 0.87 | CYP4F2 (0.50) | CYP4F2CYP4A11CETPCYP2C19MEN1 | |
| SCHEMBL23384 | 0.85 | CYP4F2 (0.49) | CYP4F2CYP4A11CETPCYP2C19MEN1 | |
| SCHEMBL23309175 | 0.84 | CYP4F2 (0.93) | CYP4F2CYP4A11CETPNPSR1MAPT | |
| SCHEMBL21399965 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11CETPMAPTMEN1 | |
| SCHEMBL20807519 | 0.84 | CYP4F2 (0.65) | CYP4F2CYP4A11CETPNPSR1MAPT | |
| SCHEMBL14858595 | 0.84 | CYP4F2 (0.65) | CYP4F2CYP4A11CETPNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789143-A | Antiproliferative based on pyrimidine | G1治疗公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-104940202-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-107936039-A | Tricyclic condensed thiophene derivant as JAK inhibitor | 因赛特公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-104918945-B | Tricyclic fused thiophene derivatives as JAK inhibitors | 因赛特公司 | 2018-01-05 | — | — | CN | disclosed |