Hydrazine

Hydrazine

SCHEMBL28200066

Clc1ccc(Cl)c(Cl)c1.NN

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.88
TSHR P16473 7/20 0.57
CYP3A4 P08684 5/20 0.57
TDP1 Q9NUW8 4/20 0.50
HSD17B10 Q99714 3/20 0.50
ALDH1A1 P00352 2/20 0.50
AHR P35869 2/20 0.50
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
MAPK1 P28482 1/20 0.46
ALOX15 P16050 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
IDO1 P14902 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL28200142 0.97 TP53 (0.82) TP53TSHRCYP3A4TDP1HSD17B10
SCHEMBL29349499 0.94
SCHEMBL8873179 0.94 TP53 (1.00) TP53TSHRCYP3A4TDP1HSD17B10
SCHEMBL22730 0.94
SCHEMBL11661765 0.90 TP53 (0.93) TP53TSHRCYP3A4TDP1HSD17B10
SCHEMBL5318805 0.90 TP53 (0.93) TP53TSHRCYP3A4TDP1HSD17B10
SCHEMBL7641130 0.90 TP53 (0.93) TP53TSHRCYP3A4TDP1HSD17B10
Potassium SCHEMBL29653750 0.90 TP53 (0.93) TP53TSHRCYP3A4TDP1HSD17B10
SCHEMBL30433206 0.90 TP53 (0.93) TP53TSHRCYP3A4TDP1HSD17B10
Water SCHEMBL27492714 0.90 TP53 (0.93) TP53TSHRCYP3A4TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed