Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28200719

COc1ccc(Cl)c(NN)c1.S

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
NQO2 P16083 1/20 0.45
MAPT P10636 4/20 0.44
ALDH1A1 P00352 2/20 0.44
SRC P12931 3/20 0.43
P2RX7 Q99572 1/20 0.42
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
HTR2A P28223 2/20 0.39
SLC6A4 P31645 2/20 0.39
LMNA P02545 2/20 0.39
POLB P06746 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
KCNH2 Q12809 1/20 0.39
GAA P10253 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862866 0.98 TDP1 (0.51) TDP1NQO2MAPTALDH1A1SRC
Hydrochloric Acid SCHEMBL20984545 0.96 TDP1 (0.50) TDP1NQO2MAPTALDH1A1SRC
Bromide SCHEMBL20984474 0.96 TDP1 (0.54) TDP1NQO2MAPTALDH1A1SRC
Phosphine SCHEMBL28200851 0.96 TDP1 (0.50) TDP1NQO2MAPTALDH1A1SRC
Oxalic Acid SCHEMBL28374121 0.88 TDP1 (0.58) TDP1NQO2MAPTALDH1A1P2RX7
Sulfuric Acid SCHEMBL20984891 0.88 TDP1 (0.51) TDP1NQO2MAPTALDH1A1P2RX7
Phosphoric Acid SCHEMBL28373873 0.88 TDP1 (0.51) TDP1NQO2MAPTALDH1A1P2RX7
Nitric Acid SCHEMBL28885949 0.85 TDP1 (0.49) TDP1MAPTALDH1A1P2RX7HDAC1
SCHEMBL10908890 0.82 NQO2 (0.46) TDP1NQO2MAPTALDH1A1HSP90AA1
Hydrochloric Acid SCHEMBL20984148 0.81 NQO2 (0.45) TDP1NQO2MAPTALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed