SCHEMBL28201078

SCHEMBL28201078

CN1C(C)(C)CC(OC(=O)C(=O)O)CC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
KMT2A Q03164 2/20 0.38
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
GAA P10253 3/20 0.34
HTT P42858 1/20 0.34
CYP2D6 P10635 1/20 0.34
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ESR1 P03372 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.30
APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5606458 0.90 TSHR (0.37) TSHRKMT2ANFKB1CYP2C19GAA
SCHEMBL30910017 0.85 GAA (0.47) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL25387445 0.84 TSHR (0.40) TSHRKMT2ANFKB1CYP2C19GAA
SCHEMBL2811158 0.83 TSHR (0.37) TSHRKMT2ANFKB1CYP2C19GAA
SCHEMBL14647653 0.83 TSHR (0.34) TSHRKMT2ANFKB1CYP2C19GAA
SCHEMBL4921204 0.83 TSHR (0.37) TSHRKMT2ANFKB1CYP2C19GAA
SCHEMBL6714702 0.82 TSHR (0.37) TSHRKMT2ANFKB1CYP2C19GAA
SCHEMBL8854706 0.81 TSHR (0.39) TSHRKMT2ANFKB1CYP2C19GAA
SCHEMBL67638 0.81 TSHR (0.39) TSHRKMT2ANFKB1CYP2C19GAA
Hydrochloric Acid SCHEMBL9794751 0.81 GAA (0.35) TSHRKMT2ANFKB1CYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107735453-A Poly carbonate resin composition 帝人株式会社 2018-02-23 CN disclosed