Cholesterol

Cholesterol

SCHEMBL28201162

C=Cc1ccccc1.CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.80

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OSBP P22059 6/20 0.80
RORC P51449 5/20 0.80
OSBP2 Q969R2 3/20 0.80
USP2 O75604 1/20 0.80
LMNA P02545 1/20 0.80
ABCB1 P08183 1/20 0.80
CYP46A1 Q9Y6A2 1/20 0.80
GRIN1 Q05586 5/20 0.70
GRIN2A Q12879 5/20 0.70
GRIN2B Q13224 4/20 0.70
NR1H3 Q13133 6/20 0.69
TSHR P16473 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
F2 P00734 1/20 0.66
POLB P06746 1/20 0.66
DPP4 P27487 1/20 0.66
CRYAB P02511 1/20 0.66
HMGCR P04035 1/20 0.66
ITGB3 P05106 1/20 0.66
ITGAV P06756 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cholesterol SCHEMBL27942138 0.91 OSBP (0.96) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL4730755 0.91 OSBP (0.88) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL10570659 0.91 OSBP (0.91) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL27893800 0.91 OSBP (0.98) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL2460866 0.91 OSBP (0.98) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL27593395 0.90 OSBP (0.86) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL27631455 0.90 OSBP (0.86) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL22341482 0.90 OSBP (0.96) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL22341486 0.90 OSBP (0.96) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL15542256 0.90 OSBP (0.96) OSBPRORCOSBP2USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107740291-A A kind of dyestuff of CVC fabrics and preparation method thereof 安徽亚源印染有限公司 2018-02-27 CN disclosed
CN-107740290-A One dyestuff and preparation method thereof for growing flax people's cotton interwoven fabric 安徽亚源印染有限公司 2018-02-27 CN disclosed