Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201023 | 0.91 | TDP1 (0.64) | SMN1; SMN2EPHX2HSD11B1MGLLTDP1 | |
| SCHEMBL1244906 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2EPHX2HSD11B1MGLLTDP1 | |
| SCHEMBL20804546 | 0.83 | SMN1; SMN2 (0.90) | SMN1; SMN2HSD11B1PLA2G7ALDH1A1KDM4E | |
| SCHEMBL13504099 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2EPHX2HSD11B1MGLLTDP1 | |
| Hydrochloric Acid SCHEMBL4618193 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2EPHX2HSD11B1MGLLTDP1 | |
| SCHEMBL4387885 | 0.80 | SMN1; SMN2 (0.90) | SMN1; SMN2HSD11B1TDP1PLA2G7ALDH1A1 | |
| SCHEMBL31065708 | 0.80 | SMN1; SMN2 (0.90) | SMN1; SMN2HSD11B1TDP1PLA2G7ALDH1A1 | |
| SCHEMBL28201026 | 0.80 | POLB (0.53) | SMN1; SMN2EPHX2HSD11B1MGLLTDP1 | |
| SCHEMBL2134021 | 0.80 | ABL1 (0.53) | SMN1; SMN2EPHX2HSD11B1MGLLTDP1 | |
| SCHEMBL13504097 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2EPHX2HSD11B1MGLLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652270-A | 2‑（4 morpholinyls）4,6 disubstituted pyrimidines/s-triazine compound and its salt and application | 西安交通大学 | 2018-02-02 | — | — | CN | disclosed |