SCHEMBL28202

SCHEMBL28202

CC(C)(C)CO[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141380 0.78 CYP2C19 (0.33)
SCHEMBL6007966 0.77
SCHEMBL3104027 0.77
SCHEMBL11503738 0.77
SCHEMBL3722570 0.77
SCHEMBL104113 0.75
SCHEMBL6141354 0.73
SCHEMBL7631314 0.73
SCHEMBL5325483 0.73
SCHEMBL9470392 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3328 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114014878-B Conjugated alkenyl zinc reagent, preparation method and application thereof 南开大学 2024-06-07 CN claimed
CN-116535439-B Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof 南开大学 2024-05-28 CN claimed
CN-116535439-A Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof 南开大学 2023-08-04 CN claimed
WO-2023142725-A1 CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF 南开大学 2023-08-03 WO claimed
CN-116003462-A Silicon-based substituted chiral amine and preparation method and application thereof 南开大学 2023-04-25 CN claimed
CN-115850328-A Diphosphine ligand with cyclopropane skeleton and cobalt complex thereof, preparation method and application 南开大学 2023-03-28 CN claimed
CN-114621311-A Method for synthesizing cyclic heptapeptide Mortiamides and analogues thereof under assistance of DPKO carrier 西北工业大学 2022-06-14 CN claimed
US-20220162219-A1 Chiral Bisamino-Ether Compounds, And Method of Preparation and Use Thereof UNIV JINAN (CN) 2022-05-26 US claimed
CN-114249725-A Preparation method and application of 2-imine-9-aryl substituted phenanthroline and iron complex thereof 南开大学 2022-03-29 CN claimed
CN-114014879-A Optically active biaryl borane adduct and preparation method and application thereof 南开大学 2022-02-08 CN claimed
US-20010047006-A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis AGOURON PHARMACEUTICALS, INC. 2001-11-29 US claimed
WO-2001079167-A2 ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2001-10-25 WO claimed
WO-2001040189-A1 ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2001-06-07 WO claimed
EP-0645378-B1 Condensed seven- or eight-membered heterocyclic compounds useful as squalene synthetase inhibitors TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2000-08-23 EP claimed
US-5698691-A ANTICHOLESTEROL AGENT; SYNTHETASE INHIBITOR; FUNGICIDE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-12-16 US claimed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 EP claimed
EP-0467183-A1 Herbicides based on sulfonylated (thio)carbamic acid esters, sulfonylated carbamic acid esters and process for their preparation BAYER AG (DE) 1992-01-22 EP claimed
US-4962104-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US claimed
EP-0102163-B1 TRIAZOLE DERIVATIVES AND COMPOSITIONS CONTAINING THE SAME CHEVRON RESEARCH COMPANY (US) 1987-04-01 EP claimed
US-4584008-A FUNGICIDES AND PLANT GROWTH REGULATORS CHEVRON RESEARCH COMPANY (US) 1986-04-22 US claimed