Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258042 | 0.88 | TSHR (0.52) | TSHRLMNAKDM4ESLC1A1ALDH1A1 | |
| Dimethyl Succinate SCHEMBL29369082 | 0.87 | TSHR (0.65) | TSHRLMNAKDM4ESLC1A1ALDH1A1 | |
| Dimethyl Succinate SCHEMBL10213 | 0.83 | TSHR (1.00) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL28054469 | 0.83 | TSHR (1.00) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL8279035 | 0.82 | TSHR (0.65) | TSHRLMNAKDM4ESLC1A1ALDH1A1 | |
| SCHEMBL28300022 | 0.82 | TSHR (0.43) | TSHRSLC1A1ALDH1A1KMT2AHSD17B10 | |
| Dimethyl Succinate SCHEMBL28197319 | 0.80 | TSHR (0.81) | TSHRLMNAKDM4ESLC1A1ALDH1A1 | |
| SCHEMBL27687738 | 0.80 | MGAM (0.71) | TSHRLMNAKDM4ESLC1A1ALDH1A1 | |
| Dimethyl Succinate SCHEMBL7778900 | 0.80 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL29248752 | 0.80 | TSHR (0.93) | TSHRLMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698438-A | A kind of method for preparing the more formic acid analog derivatives of aromatic hydrocarbons | 朱翠英 | 2018-02-16 | — | — | CN | disclosed |