Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | FES | P07332 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148244 | 0.86 | STAT3 (0.39) | STAT3STAT1SOAT1CYP3A4CYP2D6 | |
| Benzene SCHEMBL28628071 | 0.85 | STAT3 (0.52) | STAT3STAT1PDPK1CDK1CDK2 | |
| SCHEMBL29827170 | 0.85 | STAT3 (0.52) | STAT3STAT1PDPK1CDK1CDK2 | |
| SCHEMBL473160 | 0.85 | STAT3 (0.52) | STAT3STAT1PDPK1CDK1CDK2 | |
| Hydrochloric Acid SCHEMBL28432951 | 0.84 | STAT3 (0.51) | STAT3STAT1PDPK1CDK1CDK2 | |
| SCHEMBL11566885 | 0.84 | STAT3 (0.51) | STAT3STAT1PDPK1CDK1CDK2 | |
| SCHEMBL30657449 | 0.84 | STAT3 (0.51) | STAT3STAT1PDPK1CDK1CDK2 | |
| SCHEMBL1275380 | 0.84 | STAT3 (0.51) | STAT3STAT1PDPK1CDK1CDK2 | |
| SCHEMBL11331093 | 0.84 | STAT3 (0.51) | STAT3STAT1PDPK1CDK1CDK2 | |
| SCHEMBL31314990 | 0.84 | STAT3 (0.51) | STAT3STAT1PDPK1CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107828066-A | Porphyrin modified metal organic frame nano material of four sulfydryls and its production and use | 山东师范大学 | 2018-03-23 | — | — | CN | disclosed |
| CN-107759803-A | A kind of four sulfydryl porphyrin compounds and its production and use | 山东师范大学 | 2018-03-06 | — | — | CN | disclosed |