Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19962679 | 0.77 | MEN1 (0.44) | PARP10PARP11ARPARP1KDM1A | |
| SCHEMBL2880311 | 0.76 | PARP10 (0.41) | PARP10PARP11PARP1PNMTASIC3 | |
| SCHEMBL4870530 | 0.75 | PARP10 (0.43) | PARP10PARP11PARP1PNMTASIC3 | |
| SCHEMBL3345163 | 0.73 | PARP10 (0.39) | PARP10PARP11PARP1PNMTASIC3 | |
| SCHEMBL4869350 | 0.72 | PARP10 (0.41) | PARP10PARP11PARP1PNMTASIC3 | |
| SCHEMBL12525236 | 0.72 | PARP10 (0.41) | PARP10PARP11PARP1PNMTASIC3 | |
| SCHEMBL8648955 | 0.72 | PARP10 (0.41) | PARP10PARP11PARP1PNMTASIC3 | |
| SCHEMBL25209388 | 0.70 | CES1 (0.40) | PARP10PARP11ARPARP1PNMT | |
| SCHEMBL31238797 | 0.70 | CES1 (0.40) | PARP10PARP11ARPARP1PNMT | |
| SCHEMBL24069033 | 0.69 | PARP10 (0.31) | PARP10PARP11HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107750250-A | Indolone compounds and their use as ampa receptor modulators | 詹森药业有限公司 | 2018-03-02 | — | — | CN | disclosed |